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There's really no way to know if double mutation amps you up. Bradford got lucky (or unlucky in the sense that he's skin and bones now), but who's to say someone else won't mutate into something worse off?
It's too bad Mutagen Man doesn't seem to be affected since he seems to be able to consume Mutagen without mutating further. A double mutation might have been something better than waiting for years on Donnie. At the very least he should be turned into something that can walk around and talk again, and not just a random mass of organs.
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