I actually have a bit of a story involving it
My brother broke his leg in February of 2014 (spiral fracture in his thigh that was centimeters from needing surgery). During that time, some of House was on Netflix, so he was laid up watching that a lot of the time he was on the couch.
Of course the whole experience fundamentally changed him and I'm pretty sure he ended up absorbing a lot of House's personality into his own. He's writing a TV show that was initially inspired by House in the hospital drama end of it (it's an espionage show now...
I think???).
I told that story to our housemate, one of my brother's best friends. He thinks it explains a lot about him.