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Maybe dramatic effect mostly? The sort of moment where it's established that a "Drop" does the trick and so in a scene where someone "chugs down a tankard" of it puts shock upon the viewer. That sort of "he's over the edge, what is going to happen?" moment.
Maybe character effect - Bebop and Rocksteady aren't as calculating as Krang or Shredder so they get a hammer and hit everything in sight whereas Krang hits the head of the nail that he needs to hit.
It's been so long since I've seen the show I'd need to revisit the episodes you have cited to decide whether or not there was any additional story context to the "volume of mutagen used".
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