Oh yeah, now I remember the gooshy quote. Also, about Raph feeling responsible because he's Casey's best friend, I think that was hitting the nail right on the head. That's most certainly it.
As for the real vampires, I'd bet it was supposed to refer to the Vol. 1 issue as well, but almost half of Volume 1 isn't really canon (like the Souls trilogy or Spaced Out), so I don't know if Men of Shadow is canon.
As it is, Bad Moon Rising sounds a lot more interesting. Especially with beautiful vampire girls!