I wouldn't mind Chameleon actually, since he had a lot of potential after discovering Peter's identity in the late 90s/2000s that wasn't quite realised (the story where he finds out is one of the best of the post-Clone Saga era and you should read it if you haven't), he never did recover as a character from the beating MJ gave him with a baseball bat
BTW, Conway confirmed on Twitter to a fan that Regent did'nt kill the Avengers or X-Men in this universe, so yeah, it's looking that this is definitely a universe where everything from 1962-2007 happened and then it does it's own thing, borrowing elements from the last decade or so to fit the story.